You will find there's release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors inside the dorsal horn to reduce afferent suffering transmission and make analgesia. Thus, medications like clonidine that concentrate on alpha-2 receptors can influence the transmission of suffering. This doc won't contain all https://giosuea051sjy6.tdlwiki.com/user