In the LSD-sure crystal structure, the side chain of the lid residue L209EL2 kinds considerable hydrophobic contacts with both LSD and bordering residues in TMs III, IV, and V (Figure 4C). Once the lid moved aside to reveal the binding pocket in simulation, many of those contacts broke. We So https://lsd-aztec-9945432.blogoscience.com/41401582/lsd-vial-an-overview