New selective PAD4 inhibitors binding a calcium-deficient type of the PAD4 enzyme have validated the crucial enzymatic purpose of human and mouse PAD4 in equally histone citrullination and neutrophil extracellular trap development for, to our know-how, The very first time. The therapeutic possible of PAD4 inhibitors can now be explored. https://damienfrcnr.blognody.com/47596799/a-review-of-cas-1652591-81-5